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Methyl CPG, 60 caps
$ 43.00
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Nutritionist Approved
60-Day Return GuaranteeDESCRIPTION
Methyl CpG is a comprehensive formula that includes targeted amounts of five key nutrients designed to aggressively support methylation and homocysteine balance in the body. Methyl CpG provides high-concentration folate as Quatrefolic® - 100% 5-MTHF, the biologically active form, and trimethyl glycine. The formula includes key methylation vitamins B2, B6 and B12 (methylcobalamin). This specific blend of methyl donors promotes DNA repair, homocysteine balance, neurotransmitter production, hormone balance and optimal detoxification.
- Supports Optimal Methylation and Cardiovascular Health
- Supports Healthy Homocysteine Levels
- Increases Neurotransmitter Production
- Supports Primary Detoxification Pathways
- Promotes DNA Repair
INGREDIENTS
Ingredients:
Riboflavin (Vitamin B2 USP)
Vitamin B6(as Pyridoxine Hydrochloride USP)
Folate (from 2,000 mcg as Quatrefolic® (6S)-5-Methyltetrahydrofolic acid glucosamine salt
Vitamin B12 (as Methylcobalamin)
Betaine (Trimethylglycine)
Other Ingredients: Natural Vegetable Capsules, Microcrystalline Cellulose, Magnesium Stearate, Stearic Acid, Calcium Silicate, and Silicon Dioxide
Formulated to be free of allergens derived from: Gluten, corn, yeast, artificial colors and flavors.
DIRECTIONS
Serving Size: 1 capsule
Servings per container: 60
Suggested Use: 1 capsule per day or as recommended by your healthcare professional.
If you are pregnant or nursing, consult your physician before taking this product.
Keep container tightly closed. Store are room temperature. Keep out of reach of children.
LEARN MORE
Folate
Folate is a water soluble member of the B complex vitamins that is critical for maintaining optimal methylation. Folate is abundantly found in foods such as fruits and dark leafy vegetables but, can be easily destroyed by cooking or processing. The bioactive form of folate is 5-methyltetrahydrofolate (5-MTHF). 5-MTHF is required as a methyl group donor for several processes, including the production of mood regulating neurotransmitters, the synthesis of melatonin, and DNA production and repair.
Vitamin B12
Vitamin B12 works with folate in many body processes, including the synthesis of DNA, red blood cells and supporting health of the myelin sheath, the insulating exterior that surrounds nerve cells. B12 is found primarily in animal foods. Vegetarians and the elderly run the highest risk of B12 deficiency. Methylcobalamin is the preferred form of B12, as it is the biologically active form of B12 and supports the up-regulation of methylation pathways.
Vitamin B6
Vitamin B6 is a crucial B vitamin that is involved in the production of proteins in the body, neurotransmitters that help regulate mood, red blood cell formation and the proper functioning of the immune system. B6 is required for more than 60 different enzymatic reactions that occur in the body. Vitamin B6 works along with 5-MTHF and B12 in the recycling of homocysteine. B6 also supports a healthy cardiovascular system by promoting healthy platelet aggregation and aids in maintaining normal blood pressure.
Vitamin B2
Optimizing B2 status helps support healthy blood pressure, particularly in patients with genetic mutations (MTHFR 677 > T polymorphism).
Betaine (Trimethylglycine)
As a methyl donor, trimethylglycine supports liver function, including detoxification pathways. Trimethylglycine has been shown to be beneficial in protecting against fat accumulation in the liver, due to its lipotropic properties (donating a methyl group to aid in the transport of fat out of the liver). Trimethylglycine also works alongside B2, B6, B12 and folate in maintaining normal homocysteine levels.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
References
1. 5-methyltetrahydofolate. Altern Med Review 2006; 11(4).
2. Murray MT. Encyclopedia of Nutritional Supplements. (1996); Prima Publishing: Rocklin, CA. 3. Ayback M. Effect of oral pyroxidine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension. Arzneim Forsh 1995;45:1271- 1273.
4. Levene CI, Murray JC. The aetiological role of maternal B6 deficiency in the development of atherosclerosis. Lancet 1977;i:628-629.
5. Hustad S, Ueland PM, Vollset SE, Zhang Y, Bjorke-Monsen AL, Schneede J. Riboflavin as a determinant of plasma total homocysteine: effect modification by the methylenetetrahydrofolate reductase C677T polymorphism. Clin Chem 2000; 46:1065–1071.
6. Horigan G, McNulty H, Ward M, Strain JJ, Purvis J, Scott J. Riboflavin lowers blood pressure in cardiovascular disease patients homozygous for the 677C > T polymorphism in MTHFR. J Hypertension 2012;28(3):478-486.
7. Junnila M, Barak AJ, Beckenhauer HC, Rahko T. Betaine reduces hepatic lipidosis induced by carbon tetracholoride in Sprague-Dawley rats. Vet Hum Toxicol 1998;40:263-6.
8. Kim SK, Kim YC, Kim YC. Effects of singly administered betaine on hepatotoxicity of chloroform in mice. Food Chem Toxicol 1998;36:655-61.
9. Barak AJ, Beckenhauer HC, Matti J, Tuma DJ. Dietary betaine promotes generation of hepatic S-adenosylmethione and protects the liver from ethanol-induced fatty infiltration. Alcohol Clin Exp Res 1993;17:552-5.
2. Murray MT. Encyclopedia of Nutritional Supplements. (1996); Prima Publishing: Rocklin, CA. 3. Ayback M. Effect of oral pyroxidine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension. Arzneim Forsh 1995;45:1271- 1273.
4. Levene CI, Murray JC. The aetiological role of maternal B6 deficiency in the development of atherosclerosis. Lancet 1977;i:628-629.
5. Hustad S, Ueland PM, Vollset SE, Zhang Y, Bjorke-Monsen AL, Schneede J. Riboflavin as a determinant of plasma total homocysteine: effect modification by the methylenetetrahydrofolate reductase C677T polymorphism. Clin Chem 2000; 46:1065–1071.
6. Horigan G, McNulty H, Ward M, Strain JJ, Purvis J, Scott J. Riboflavin lowers blood pressure in cardiovascular disease patients homozygous for the 677C > T polymorphism in MTHFR. J Hypertension 2012;28(3):478-486.
7. Junnila M, Barak AJ, Beckenhauer HC, Rahko T. Betaine reduces hepatic lipidosis induced by carbon tetracholoride in Sprague-Dawley rats. Vet Hum Toxicol 1998;40:263-6.
8. Kim SK, Kim YC, Kim YC. Effects of singly administered betaine on hepatotoxicity of chloroform in mice. Food Chem Toxicol 1998;36:655-61.
9. Barak AJ, Beckenhauer HC, Matti J, Tuma DJ. Dietary betaine promotes generation of hepatic S-adenosylmethione and protects the liver from ethanol-induced fatty infiltration. Alcohol Clin Exp Res 1993;17:552-5.