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CholestePure Plus II, 120 caps

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CholestePure Plus II provides a unique blend of phytosterols, berberine and clinically studied bergamot extract to promote healthy lipid metabolism and overall cardiometabolic health.

  • Supports phytosterol intake and overall cardiovascular health
  • Promotes healthy cholesterol metabolism



Serving Size: 2 capsules
Servings per container: 60


  • Phytosterols (from PhytoPin® pine (Pinus pinaster) phytosterol complex) 500 mg 
  • Berberine HCl 400 mg
  • Bergavit® 40 bergamot (Citrus bergamia) extract (fruit) 160 mg 

Other ingredients: vegetarian capsule (cellulose, water)

Gluten Free | Dairy Free | Vegan | Vegetarian | Soy Free | Non-GMO

Bergavit®40 is a registered trademark of Bionap S.r.l.

PhytoPin®is a registered trademark DRT and licensed to Pure Encapsulations.



Directions: 2 capsules, 1-2 times daily, with meals.

Warning: Not to be taken by pregnant or lactating women.

Warning: Individuals taking this product with anti-hyperglycemic medications may require blood glucose monitoring. Berberine may be contraindicated with blood pressure and blood thinning medications. Consult your physician for more information



Phytosterols are structural homologs of cholesterol that occur naturally in many plant foods. Over 30 years of research and 40 clinical trials suggest that phytosterols provide significant support for healthy lipid profiles.

Well-established benefits of phytosterols on lipid balance stem primarily from competition with cholesterol for occupancy in micelles, particles that carry cholesterol across the intestinal epithelium into the systemic circulation. Through this mechanism, phytosterols promote excretion of cholesterol in the form of bile acids. Research indicates that the pine-derived phytosterols offered in this formula are comparable to phytosterols from other sources.

Bergamot is a citrus fruit containing two newly discovered derivatives of the flavonoids hesperidin and naringenin. In the liver, these unique molecules bind and modulate an enzyme known as HMG CoA reductase, which plays a central role in lipid biosynthesis. These unique compounds also target enzymes, transcription factors and genes involved in lipid metabolism. In a study involving 192 volunteers, bergamot juice maintained healthy cholesterol and lipid levels in the normal range over a 30-day period. In a separate study of 80 subjects, 150 mg of flavonoids from Bergavit® 40 bergamot extract supported healthy lipid and glucose profiles over a six-month period.

Berberine supports cardiometabolic health through a variety of mechanisms, including support for glucose and lipid metabolism, antioxidant defenses, and cytokine production. In a randomized, placebo-controlled trial involving 116 subjects, berberine provided statistically significant support for glucose and lipid and metabolism. It also helps maintain endothelial function by promoting healthy vascular cell adhesion molecule-1 (VCAM-1) expression and healthy iNOS activity.

What Is The Source?

PhytoPin® phytosterol complex is derived from pine (Pinus pinaster). Bergavit® extract is derived from bergamot (Citrus bergamia) fruit and standardized to contain 39% flavonoids. Berberine HCl is derived from Phellodendron amurense bark and Sargent’s barberry (Berberis sargentiana).


These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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