NAC-600 contains pharmaceutical grade N-acetyl-L-cysteine (NAC) for supporting glutathione synthesis in the body, a key tripeptide that has important antioxidant roles in humans.NAC is an acetylated version of the amino acid L-cysteine, which is the limiting factor to glutathione production since it is rarely found in foods.
Given the importance of sufficient glutathione levels in the body for supporting overall health and longevity, supplementation with NAC-600 can benefit users in a variety of ways. The most relevant researched-backed benefits derived from supplementation with NAC-600 include:
●Supports metabolic reactions in body systems, especially the immune, nervous, respiratory, and gastrointestinal systems
●Acts as an antioxidant in the body to regulate oxidative stress
●Supports nitric oxide production and vascular function
Serving Size: 1 Capsule Servings per Container: 60
Directions: Take one capsule daily or as directed by your healthcare practitioner.
Caution: If you are pregnant, nursing, or taking medication, consult your healthcare practitioner before use. Keep out of reach of children.
Storage: Store in a cool, dry place.
How NAC-600 Works Much of the L-cysteine ingested through diet and supplementation is suggested to be lost to first-pass metabolism.4 This is where NAC comes into play, as its structural difference makes it more resistant to metabolism. Thus more L-cysteine can be distributed to the body (resulting in increased glutathione production).
Moreover, NAC supplementation increases glutathione concentrations in the body more than supplementing with glutathione alone since glutathione is rapidly broken down by the intestines. As alluded to earlier, glutathione serves as a crucial antioxidant throughout the body by neutralizing free radicals and reactive oxygen species. It has also been shown that glutathione plays a role in regulating the nitric oxide cycle, which is critical for proper blood flow and vascular function.
Lastly, glutathione is involved in a multitude of metabolic reactions affecting every system in the body, especially the nervous system, immune system, and gastrointestinal system. Thus, NAC-600 acts to support nominal glutathione concentrations in the body and many critical cellular functions.
Statements contained herein have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent disease.
1. Dringen, R. (2000-12-01). “Metabolism and functions of glutathione in brain”. Progress in Neurobiology. 62(6): 649–671.
2. Meister, A. (1991). Glutathione deficiency produced by inhibition of its synthesis, and its reversal; applications in research and therapy. Pharmacology & therapeutics, 51(2), 155-194.
3. Atkuri, K. R., Mantovani, J. J., Herzenberg, L. A., & Herzenberg, L. A. (2007). N-Acetylcysteine—a safe antidote for cysteine/glutathione deficiency. Current opinion in pharmacology, 7(4), 355-359.
4. Frank Giorlando MBBS, B. (2011). N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action. Journal of psychiatry & neuroscience: JPN, 36(2), 78.
5. Sjödin, K., Nilsson, E., Hallberg, A., & Tunek, A. (1989). Metabolism of N-acetyl-l-cysteine Some structural requirements for the deacetylation and consequences for the oral bioavailability. Biochemical pharmacology, 38(22), 3981-3985.
6. Witschi, A., Reddy, S., Stofer, B., & Lauterburg, B. H. (1992). The systemic availability of oral glutathione. European journal of clinical pharmacology, 43(6), 667-669.