PRM Resolve, 60 caps

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PRM Resolve  (Pro-Resolving Mediators) 

PRM Resolve is a proprietary formula providing pro-resolving lipid mediators (PRMs), which help encourage “specialized pro-resolving mediator” (SPM) production in the body. SPMs are unique molecules that evoke novel pro-resolving mechanisms and play extensive roles in host defense, tissue remodeling, and organ support.

SPM production is affected by several factors, particularly nutrition, health status, genetics, and lifestyle choices. Lack of SPM production may hinder the body’s ability to effectively resolve an immune response, thereby impacting health and well-being

An expansive and evolving body of preclinical research suggests that SPMs play a pivotal role in resolving immune responses

  • PRM Resolve offers a multifunctional approach to promote a healthy response to physical stress and support challenges that the body may face
  • Specialized pro-resolving mediators are a novel genus of molecules that play a key role in resolving (completing) a healthy immune response
  • SPMs work to support healthy immune cell activities during the “resolution phase” of an immune response.



Serving Size: 2 capsules

Servings per container: 30

2 Softgels Supplies:

Ingredient Amount Daily Value
Calories 25
Total Fat 2 g 3%*
Cholesterol 10 mg 3%*
Protein <1 g  
Marine Lipid Concentrate 2.1 g **
Total Omega-3 Fatty Acids 1,200 mg **
   EPA (Eicosapentaenoic Acid) 580 mg **
   DHA (Docosahexaenoic Acid) 420 mg **
   Additional Omega-3 Fatty Acids 200 mg **
Total PRMs [including 18-hydroxyeicosapentaenoic acid (18-HEPE), 17-hydroxydocosahexaenoic acid (17-HDHA), 14-hydroxydocosahexaenoic acid (14-HDHA)] 400 mcg **
* Percent Daily Values (DV) are based on a 2,000 calorie diet.    
** Daily Value (DV) not established.


Other Ingredients:Highly concentrated omega-3 marine oil (anchovy, sardine, squid, and mackerel), capsule shell (gelatin, glycerin, purified water), natural lemon flavor, natural mixed tocopherols.
Contains: Fish (anchovy, sardine, squid, and mackerel).


Recommendations:Take two softgels daily or as directed by your healthcare practitioner.

If pregnant, nursing, or taking nutritional supplements or medications, consult your healthcare practitioner before use. Keep out of reach of children.



How PRM Resolve Works: The discovery of the structurally distinct families of signaling molecules— namely resolvins, maresins, and protectins, collectively termed “specialized pro-resolving mediators” (SPMs)—led scientists to a newfound interest in the mechanisms that promote a healthy immune response (which thereby helps the body attain homeostasis).

As research on these unique and potent molecules has grown, it’s become quite clear that they are “resolving agonists” with the potential to stimulate key cellular events that promote the completion (i.e., resolution) of a healthy immune response.

But why is resolving an immune response so crucial for health and well-being? Think of an immune response like a wildfire; it starts in a localized area and doesn’t impact much of the surroundings. However, if left unresolved, the fire rapidly spreads further and further, consequently causing significant ramifications and damage.

SPMs are much like the “fire extinguisher” in this case, helping your body return to homeostasis and removing unwanted debris, microbes, and dead immune cells from the body before the immune response can permeate further.

In short: SPMs are a revolutionary family of signaling molecules that work harmoniously to support healthy immune responses and help the body return to a healthy balance (i.e., homeostasis).


Statements contained herein have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent disease.