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WholeMune, 30 caps
$ 30.90
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Nutritionist Approved
60-Day Return GuaranteeDESCRIPTION
WholeMune primes immune cells without stimulating the immune system, making it the preferred product for season-long immune readiness.
WholeMune is formulated with Wellmune WGP®, the most well-researched, single beta glucan, proven in human clinical trials to prepare and protect the immune system from repeated and ongoing stressors. Wellmune WGP® is a highly purified, yeast-free beta glucan extract derived from Saccharomyces cerevisiae. It is standardized to contain 75% pure beta glucan and is considered the most effective single nutrient to naturally prime immune cells.
- Primes and Mobilizes Key Immune Cells
- Protects Against Immune Challenges Resulting from Ongoing Stress
- Increases Immune Vitality and Mental Clarity
- Protects Against Exercise-Induced Stress
INGREDIENTS
Ingredients: Bakers Yeast Extract (Wellmune WGP®)(Standardized to contain 75% beta-glucan); Larch Arabinogalactan (Fiber Aid™)
Does not contain: Gluten, corn, yeast, artificial colors and flavors.
DIRECTIONS
Serving Size: 1 capsule
Servings per Container: 30
Suggested Use: 1 capsule per day or as recommended by your health care professional.
Warning: If you are pregnant or nursing, consult your physician before taking this product.
Keep container tightly closed. Store at room temperature. Keep out of reach of children.
LEARN MORE
A strong immune system is integral to overall health and wellbeing. Maintaining a strong immune system can often be a challenge in today’s world- high stress levels, poor diet, lack of sleep and environmental pollutants can slow down immune response. WholeMune’s primary active ingredient is Wellmune WGP®- a natural beta 1,3/1,6 glucan derived from the cell wall of a proprietary strain of baker’s yeast (Saccharomyces cerevisiae). Once swallowed, immune cells in the gastrointestinal tract take up Wellmune WGP® and transport it to immune organs throughout the body. Specific immune cells called macrophages digest Wellmune WGP® into smaller fragments and slowly release them over a number of days. The fragments then bind to neutrophils (white blood cells), via complement receptor 3 (CR3). Neutrophils are the most abundant immune cells in the body, accounting for 60-70% of all immune cells. The activation of neurotrophils by Wellmune WGP® fragments allows these cells to move faster throughout the body, resulting in a significant boost in immune defense.
Wellmune WGP®
Beta-glucan has been recognized for its support of immune system activity for centuries and has become the subject of over 800 scientific studies. Wellmune WGP® has been shown in clinical studies to have a potent effect on immune responsiveness and to defend the system from the effects of recurring stress. Numerous studies have shown beta glucan also promotes production of antioxidant enzymes and supports immune function against microbes. In another randomized, placebo-controlled, double-blind study on the effects of four weeks of 250 mg Wellmune WGP® or 250 mg per day of rice flour placebo on the physical and psychological health of those with seasonal discomfort symptoms, Wellmune WGP® improved symptoms, overall physical health, and emotional well-being compared with placebo. Further research on medical students found a 22% reduction in the total number of days with upper respiratory symptoms in Wellmune WGP® group vs. placebo. Finally, a 28-day lifestyle study found that participants taking Wellmune WGP® reported a 34% improvement in health scores after four weeks compared with the control group as well as increased vigor, and lower fatigue, confusion and tension. Wellmune WGP® has also been found to provide post exercise protection, to maintain white cell concentrations/monocytes, improve mucosal immunity, enhance immune responses to a perceived challenge, and improved salivary IgA post exercise.
Statements contained herein have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent disease.
References
1. Tian J, Ma J, Wang S, et al. Increased expression of mGITRL on D2SC/1 cells by particulate β-glucan impairs the suppressive effect of CD4(+)CD25(+) regulatory T cells and enhances the effector T cell proliferation. Cell Immunol 2011; 270(2):183-7.
2. Senoglu N, Yuzbasioglu MF, Aral M, et al. Protective effects of N-acetylcysteine and beta-glucan pretreatment on oxidative stress in cecal ligation and puncture model of sepsis. J Invest Surg 2008; 21(5):237-43.
3. Talbott S, Talbott J. Beta 1,3/1,6 glucan decreases upper respiratory tract infection symptoms and improves psychological well-being in moderate to highly-stressed subjects. Agro FOOD Industry hi-tech 2010;21(1):21-24.
4. Talbott S, Talbott J. Effect of BETA 1, 3/1, 6 GLUCAN on upper respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med. 2009;8: 509-515.
5. K. C. Carpenter, W. L. Breslin, T. Davidson, A. Adams and B. K. McFarlin. Baker’s yeast β-glucan supplementation increases monocytes and cytokines post-exercise: implications for infection risk? 21 May 2012 by Wellmune in Clinical Research, Research. British Journal of Nutrition, FirstView Article : pp 1-9.
2. Senoglu N, Yuzbasioglu MF, Aral M, et al. Protective effects of N-acetylcysteine and beta-glucan pretreatment on oxidative stress in cecal ligation and puncture model of sepsis. J Invest Surg 2008; 21(5):237-43.
3. Talbott S, Talbott J. Beta 1,3/1,6 glucan decreases upper respiratory tract infection symptoms and improves psychological well-being in moderate to highly-stressed subjects. Agro FOOD Industry hi-tech 2010;21(1):21-24.
4. Talbott S, Talbott J. Effect of BETA 1, 3/1, 6 GLUCAN on upper respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med. 2009;8: 509-515.
5. K. C. Carpenter, W. L. Breslin, T. Davidson, A. Adams and B. K. McFarlin. Baker’s yeast β-glucan supplementation increases monocytes and cytokines post-exercise: implications for infection risk? 21 May 2012 by Wellmune in Clinical Research, Research. British Journal of Nutrition, FirstView Article : pp 1-9.