Pro Bono provides the nutritional support needed to maintain healthy bone formation. The single-serving AM and PM packets make Pro Bono convenient, while separating the calcium and strontium servings for better absorption.
Pro Bono is a targeted bone building protocol specifically designed to increase skeletal strength and help maintain healthy bone density. It provides therapeutic doses of clinically-proven, bone-stimulating nutrients in convenient, easy-to-take packets to enhance bone formation. The foundation of Pro Bono is 1,000 mg of strontium, one of the most well-researched, bone-supporting minerals proven to strengthen the bone matrix and support skeletal density. Each serving provides the most bioavailable sources of strontium, calcium, magnesium, vitamin D3, vitamin K2, boron and other trace minerals to support bone health and maintenance. In addition, Pro Bono includes a full complement of micronutrients, making an additional multivitamin unnecessary.
Convenient, Multi-faceted Bone Building Protocol
Increases Skeletal Strength
Promotes Healthy Bone Density
Improves Bone Remodeling
Provides a Comprehensive Blend of Foundational Micronutrients
Strontium is a mineral that is similar to the physical and chemical properties of calcium. Research has shown strontium to provide all natural bone support through its ability to increase the formation of osteoblasts while decreasing the formation of osteoclasts.
Nearly 99% of the calcium within the adult skeletal system exists as a complex paired with phosphorus, called hydroxyapatite. It is commonly advised that individuals past early adolescence consume 1,000 to 1,500 mg/ day from dietary or supplement sources to support bone formation. Pro Bono is formulated with calcium citrate-malate, as well as calcium hydroxyapatite, to improve absorption and support optimal bone health.
Magnesium plays a major role in bone formation as approximately 50% of magnesium found in the body is found in the bone. Magnesium plays numerous roles in bone health including increasing calcium absorption, acting as a cofactor for alkaline phosphatase activation, as well as supporting vitamin D3 conversion in the body. Magnesium deficiency is very common–many Americans fail to acquire even the estimated average requirement (EAR). Magnesium deficiency can also be exacerbated due to factors such as excess consumption of alcohol, salt, coffee, phosphoric acid in sodas, and long-term stress.
Vitamin D3 (Cholecalciferol)
Vitamin D is a steroid vitamin that is known for its role in supporting bone health and aiding in the absorption of calcium and phosphate from the GI tract.
Vitamin K is responsible for synthesizing osteocalcin, a protein involved in calcium transport and properly embedding calcium into bone tissue. Vitamin K has also been shown to decrease the activity of osteoclasts, which helps to maintain bone formation and strength. Vitamin K works synergistically with vitamin D3 to improve calcium absorption and helps to bind newly absorbed calcium to the bone matrix.
Boron supplementation reduced urinary excretion of calcium and magnesium and increased blood levels of 17 betaestradiol and testosterone in postmenopausal women in one study. Improving boron levels has been shown to support bone health.
Servings Per Container: 30
Suggested Use:2 packets per day, one AM packet in the morning and one PM packet in the evening or as recommended by your health care professional
Maintenance: 1 packet per day alternating one AM packet on odd days and one PM packet on even days or as recommended by your health care professional
Formulated to be free of allergens derived from: Gluten, yeast, artificial colors and flavors.
Warning: All forms of Vitamin K may interact with blood thinning medications. If you are taking such medicines, please consult your physician before taking this product.
Do not consume this product if you are pregnant or nursing. Consult your physician for further information.
Store at room temperature. Keep out of reach of children.
Bone mineral density (BMD) is a major determinant of bone mass and is the most commonly measured quality of bone. A number of factors contribute to bone mineral density including lifestyle factors (regular physical activity, not smoking, minimizing stress levels) and maintaining hormonal balance. Consuming a healthy diet and ensuring optimal levels of bone-building vitamins and minerals are a key therapeutic consideration for preserving bone strength.
BMD is determined by a lifelong process called bone remodeling. Bone remodeling occurs when bone tissue is removed from the skeleton (bone resorption) and new bone tissue is formed. Osteoclasts are cells involved with breaking down bone, while osteoblasts create a protein matrix primarily of collagen, resulting in the remineralization of bone and thereby promoting bone formation. While calcium is an effective starting point for promoting bone health, other nutrients are required for bone mineralization. Nutrients such as strontium, magnesium, vitamin D, K and C, B complex vitamins, and trace minerals significantly enhance bone remodeling and increase bone strength. Pro Bono® provides a comprehensive approach to bone health by offering a full spectrum of nutrients that are required in the bone mineralization process. Pro Bono® also contains nutrients that help maintain an optimal osteoclast to osteoblast ratio.
Statements contained herein have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent disease.
Due to manufacturer’s requirements, we are not allowed to ship this product to California.
1.Moise H, Chettle DR, Pejović-Milić A. Monitoring bone strontium intake in osteoporotic females self-supplementing with strontium citrate with a novel in-vivo X-ray fluorescence based diagnostic tool. Bone. 2014;61:48-54.
2. Stephen J. Genuis, Thomas P. Bouchard, “Combination of Micronutrients for Bone (COMB) Study: Bone Density after Micronutrient Intervention”, Journal of Environmental and Public Health, vol. 2012, Article ID 354151, 10 pages, 2012.
3. Maria S, Swanson MH, Enderby LT, et al. Melatoninmicronutrients Osteopenia Treatment Study (MOTS): a translational study assessing melatonin, strontium (citrate), vitamin D3 and vitamin K2 (MK7) on bone density, bone marker turnover and health related quality of life in postmenopausal osteopenic women following a one-year double-blind RCT and on osteoblast-osteoclast co-cultures. Aging (Albany NY). 2017;9(1):256-285.
4. Patrick Lyn. Comparative absorption of calcium sources and calcium citrate malate prevention for osteoporosis. Altern Med Review 1999;4(2):74-85.
5. Moshfegh A, Goldman J, Ahuja J, Rhodes D, LaComb R. 2009. What We Eat in America, NHANES 2005-2006: Usual Nutrient Intakes from Food and Water Compared to 1997 Dietary Reference Intakes for Vitamin D, Calcium, Phosphorus, and Magnesium. U.S. Department of Agriculture, Agricultural Research Service.
6. Johnson S. The multifaceted and widespread pathology of magnesium deficiency. Med Hypotheses 2001; 56(2): 163-70.
7. Stendig-Lindberg G, Tepper R, Leichter I. Trabecular bone density in a two year controlled trial of peroral magnesium in osteoporosis. Magnes Res 1993; 6:155-163.